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Myasthenia Gravis
| Name: | Myasthenia Gravis |
| Definition: | A disorder of neuromuscular transmission characterized by weakness of cranial and skeletal muscles. Autoantibodies directed against acetylcholine receptors damage the motor endplate portion of the NEUROMUSCULAR JUNCTION, impairing the transmission of impulses to skeletal muscles. Clinical manifestations may include diplopia, ptosis, and weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles. THYMOMA is commonly associated with this condition (MeSH). |
| Synonym(s): | Myasthenia Gravis, Generalized |
| Super-category: | Neuromuscular Junction Diseases |
| Defining citation: | Adams et al., Principles of Neurology, 6th ed, p1459 |
| Id: | birnlex_12593 |
| Link to OWL / RDF: | Download this content as OWL/RDF |
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Subcategories
This category has the following 3 subcategories, out of 3 total.
A
M
N
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| Created | 5 October 2007 + |
| CurationStatus | uncurated + |
| DefiningCitation | Adams et al., Principles of Neurology, 6th ed, p1459 + |
| Definition | A disorder of neuromuscular transmission c … A disorder of neuromuscular transmission characterized by weakness of cranial and skeletal muscles. Autoantibodies directed against acetylcholine receptors damage the motor endplate portion of the NEUROMUSCULAR JUNCTION, impairing the transmission of impulses to skeletal muscles. Clinical manifestations may include diplopia, ptosis, and weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles. THYMOMA is commonly associated with this condition (MeSH). nly associated with this condition (MeSH). |
| DefinitionSource | MeSH + |
| Id | birnlex_12593 + |
| Label | Myasthenia Gravis + |
| ModifiedDate | 30 May 2009 + |
| Synonym | Myasthenia Gravis +, and Generalized + |