Category:Myasthenia Gravis

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Name: Myasthenia Gravis
Definition: A disorder of neuromuscular transmission characterized by weakness of cranial and skeletal muscles. Autoantibodies directed against acetylcholine receptors damage the motor endplate portion of the NEUROMUSCULAR JUNCTION, impairing the transmission of impulses to skeletal muscles. Clinical manifestations may include diplopia, ptosis, and weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles. THYMOMA is commonly associated with this condition (MeSH).
Synonym(s): Myasthenia Gravis, Generalized
Super-category: Neuromuscular Junction Diseases
Defining citation: Adams et al., Principles of Neurology, 6th ed, p1459
Id: birnlex_12593
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