Category:Dentate gyrus IS-III cell
From NeuroLex
| Name: | Dentate gyrus IS-III cell |
| Definition: | The Dentate Gyrus MOPP cell (molecular layer perforant path-associated cell) is a interneuron in hippocampal formation. It is located deep in the DG molecular layer, has a multipolar or triangular cell body and gives rise to an axon that produces a substantial terminal plexus largely limited to the outer two thirds of the DG molecular layer. |
| Abbreviation | DG MOPP |
| Super-category: | neuron |
| Defining citation: | Page 15. Scharfman, Helen E. "The dentate gyrus : a comprehensive guide to structure function and clinical implications". |
| PMID: | PMID 8589792, PMID 17093119 |
| Id: | nlx_cell_091003 |
| Link to OWLRDF: | Download this content as OWL/RDF |
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“axonal and dendritic trees of this cell type are largely limited to the outer two-thirds of the dentate molecular layer and thus was named molecular layer perforant path-associated cell (MOPP) by Han et al. (1993). Smooth dendrites that originate from a soma in deep stratum moleculare ascend to reach the hippocampal fissure and span an area over 800 um in transverse length...The majority of collaterals run perpendicular to granule cell dendrites and arborize profusely in a terminal cloud that extends beyond the upper blade of the dentate gyrus (Fig. 9)...”..form symmetrical synapses mostly with spiny distal of granule cells (Fig 10; Halasy and Somogyi, 1993b).
Ref: Freund & Buzsaki, 1996, p365, mid left, PMID 8915675
